The Science Behind IM8

Pioneering Health With Leaders in Academia, Medicine and Space Science.

Driven by Science

Meet The Brilliant Minds Behind IM8

An unparalled collaboration between academia, medicine, and space science.

Dr. Dawn Mussallem

Integrative Oncologist at Mayo Clinic

Dr. Dawn Mussallem

Integrative Oncologist at Mayo Clinic

Dr. Dawn Mussallem is a distinguished consultant in the Division of Hematology Oncology at Mayo Clinic, where she has served as a clinician for over 20 years, and an Assistant Professor of Medicine.

She is a board-certified lifestyle medicine breast specialist at The Robert and Monica Jacoby Center for Breast Health and founded the Integrative Medicine and Breast Health Program at Mayo Clinic Florida.

A stage IV cancer survivor diagnosed three months into medical school, Dr. Mussallem’s personal journey is a testament to resilience and determination.

In 2021, she underwent a heart transplant and remarkably became the first person to run a marathon one year post-transplant.

Internationally recognized for her work in cancer prevention and integrative oncology, she is a prolific speaker and author.

Her dedication to patient care and innovative approaches align perfectly with IM8's mission, making her an invaluable addition to the Medical Advisory Board.

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Dr. James L. Green

Former Chief Scientist of NASA

Dr. James L. Green

Former Chief Scientist of NASA

Dr. James L. Green is the former Chief Scientist of NASA, where he dedicated an impressive 42 years to advancing space science and exploration.

During his tenure, Dr. Green contributed to numerous groundbreaking missions, including the Mars Rover landings, the New Horizons mission to Pluto, and the Juno mission to Jupiter.

He played a pivotal role in the development of planetary defense strategies and was instrumental in fostering international collaborations for space research.

Dr. Green's extensive experience in managing large-scale scientific projects and his deep understanding of cutting-edge technologies bring a unique perspective to IM8.

His work at NASA also included leveraging space research for health innovations, such as studying the effects of space travel on the human body and accelerated aging.

His expertise in scientific innovation and strategic vision will be invaluable in advancing IM8's mission to revolutionize healthcare through precision diagnostics and personalized medicine.

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Dr. David Katz

Founding Director, Yale-Griffin Prevention Research Center

Dr. David Katz

Founding Director, Yale-Griffin Prevention Research Center

David L. Katz, MD, MPH, FACPM, FACP, FACLM, is a specialist in Internal Medicine, Preventive Medicine/Public Health, and Lifestyle Medicine, with particular expertise in nutrition.

He earned his BA at Dartmouth College (1984); his MD at the Albert Einstein College of Medicine (1988); and his MPH from the Yale University School of Public Health (1993).

Katz is the founder and former director of Yale University’s Yale-Griffin Prevention Research Center (1998-2019); Past President of the American College of Lifestyle Medicine; Founder of the non-profit True Health Initiative; and Founder of Diet ID, Inc, and Chief Medical Officer for Tangelo.

He is a Fellow of the American College of Preventive Medicine; the American College of Physicians; the American College of Lifestyle Medicine; and Morse College, Yale University.

The recipient of numerous awards for teaching, writing, and contributions to public health, Katz was a 2019 James Beard Foundation Award nominee in health journalism, is a 2023 recipient of a Lifetime Achievement Award from the Doctors’ World Gala, and has received three honorary doctorates.

He holds multiple US patents; has roughly 250 peer-reviewed publications; and has authored/co-authored 19 books to date including multiple editions of leading textbooks in nutrition, preventive medicine, and epidemiology.

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Prof. Suzanne Devkota

Director of Cedars-Sinai Human Microbiome Research Institute

Prof. Suzanne Devkota

Director of Cedars-Sinai Human Microbiome Research Institute

Prof. Suzanne Devkota is a leading expert in microbiome research and its impact on human health, with over 15 years of experience in the field.

She is an Associate Professor at Cedars-Sinai Medical Center and the Director of the Microbiome Research Institute.

Prof. Devkota’s groundbreaking work focuses on understanding the role of the gut microbiome in chronic diseases, including inflammatory bowel disease, obesity, and diabetes.

She has published extensively in top scientific journals and is a sought-after speaker at international conferences.

Prof. Devkota’s research emphasizes the critical connection between the microbiome and overall health, highlighting the potential for microbiome-based therapies.

Her insights into how diet and lifestyle influence the gut microbiome align closely with IM8's mission to advance health through innovative diagnostics and personalized medicine.

Prof. Devkota’s expertise in microbiome science will be invaluable in helping IM8 develop cutting-edge solutions to improve health outcomes and foster preventative care.

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Prof. Stephen Anton

Professor in the Department of Physiology and Aging at University of Florida

Prof. Stephen Anton

Professor in the Department of Physiology and Aging at University of Florida

Prof. Stephen Anton is a renowned expert in aging and metabolic health, with over 20 years of experience in the field.

He is a Distinguished Professor at the University of Florida with a primary appointment in the Department of Physiology and Aging.

Prof. Anton’s research focuses on the interplay between lifestyle factors, metabolic health, and aging, with a particular emphasis on the benefits of caloric restriction, intermittent fasting, and physical activity.

He has authored numerous scientific publications and is a frequent speaker at national and international conferences.

Prof. Anton’s extensive work highlights the potential of lifestyle interventions in promoting healthy aging and preventing metabolic diseases.

His insights into the mechanisms of aging and metabolic regulation are highly relevant to IM8's mission of leveraging advanced diagnostics and personalized health strategies.

Prof. Anton’s expertise is invaluable in helping IM8 develop innovative solutions to enhance healthspan and improve metabolic health outcomes.

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Dr. James DiNicolantonio

Cardiovascular Research Scientist and Doctor of Pharmacy

Dr. James DiNicolantonio

Cardiovascular Research Scientist and Doctor of Pharmacy

Dr. James DiNicolantonio is a cardiovascular research scientist and Doctor of Pharmacy, known for his influential work in the field of heart health and evidence-based nutrition. Author of several bestselling books, including The Obesity Fix and Superfuel, he has published over 300 scientific papers, focusing on the impact of nutrition on long-term health and chronic disease prevention. His work provides valuable insights into optimizing well-being through natural and scientifically supported methods.

A respected authority in the health and wellness community, Dr. DiNicolantonio’s approach centers on simplifying complex scientific concepts, making health strategies accessible to a broad audience. He advocates for a proactive approach to wellness, combining cutting-edge research with practical applications to help individuals achieve peak physical and mental performance. His focus on heart health and longevity has made him a key figure for those looking to improve their overall well-being through informed lifestyle choices.

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Science at the Heart of IM8

At IM8, our commitment to science goes beyond innovation—it’s the foundation of everything we do. A world-class team of experts from space science, medicine, and academia has united with one goal: to revolutionize wellness. We’ve pioneered CRT8™ (Cell Rejuvenation Technology 8), designed to enhance cellular rejuvenation and push the limits of what’s possible in health.

Each of our products undergoes rigorous third-party testing and clinical trials, ensuring purity, efficacy, and results you can trust. With IM8, you're getting scientifically driven core nutrition for optimal health and longevity.

IM8 and University of Oxford Begin Groundbreaking Space Experiment to Study Accelerated Aging and Longevity on-board the ISS with SpaceX

IM8 is proud to partner with the University of Oxford on a groundbreaking month-long space experiment, now underway aboard the International Space Station (ISS). Launched via SpaceX CRS-31 on November 4th 2024 at 9:29 pm EST, the mission includes sending our patent-pending Cell Rejuvenation Ingredients® (CRT8) ingredients to the ISS to study accelerated aging and longevity. By leveraging microgravity's unique environment, the experiment aims to accelerate aging processes at the cellular level and advance our understanding of longevity. Results from the space experiment are anticipated to be released in 6-8 months, offering valuable insights into longevity and cellular health.

Exploring accelerated aging
in space

This study investigates how CRT8 ingredients may counteract ‘accelerated aging’ in space. By exploring zero gravity’s effects on aging, we seek insights to advance our understanding of aging and health, showcasing our commitment to innovation in nutritional science.

Why conduct research in space?

Space offers an environment that’s unique and unreplicable on Earth. Microgravity accelerates biological processes like aging and muscle atrophy, allowing scientists to study these effects in a compressed timeframe and gain valuable insights into their mechanisms and potential mitigations.

Opportunities space offers:

Drug discoveries: Microgravity alters cellular processes, leading to breakthroughs in disease understanding and drug development.

Growing organs: Space research shows potential for growing tissues and organs for future transplantation.

Accelerated testing: Space’s accelerated aging potentially fast-tracks anti-aging compound testing and treatments.

Deep dive:
Cell Rejuvenation
Technology 8™
(CRT8)

Our premium core nutrition line is anchored by the innovative “Cell Rejuvenation Technology 8,” a patent-pending blend crafted from nature’s most powerful bioactive compounds.

Each component is chosen to enhance the body’s natural rejuvenation processes, inspired by the healing properties of the ocean and the earth.

Deep dive:
Cell Rejuvenation
Technology 8™
(CRT8)

Our premium core nutrition line is anchored by the innovative “Cell Rejuvenation Technology 8,” a patent-pending blend crafted from nature’s most powerful bioactive compounds.

Each component is chosen to enhance the body’s natural rejuvenation processes, inspired by the healing properties of the ocean and the earth.

Fucoidan

Fucoidan is a complex polysaccharide with immune-boosting, anti-inflammatory, and antioxidant properties that support overall health and wellness.

Fucoidan is a naturally occurring polysaccharide found in brown seaweed, known for its diverse health benefits. It supports the immune system by enhancing the body's natural defense mechanisms and has anti-inflammatory properties that help reduce inflammation and support overall health.
Additionally, Fucoidan offers antioxidant protection, helping to neutralize free radicals and protect cells from oxidative damage. Its potential benefits extend to supporting cardiovascular health, digestive function, and promoting overall well-being.
Incorporating Fucoidan into your regimen can enhance immune function, reduce inflammation, and provide valuable antioxidant support.
Berberine HCl

Berberine HCl is a natural compound that supports healthy blood sugar levels, improves metabolic function, and promotes cardiovascular health.

Berberine HCl is a powerful plant-derived compound known for its ability to support healthy blood sugar levels by improving insulin sensitivity and promoting glucose metabolism. It has been shown to enhance metabolic function, making it beneficial for individuals looking to manage weight and improve overall metabolic health.
Berberine also supports cardiovascular health by helping to regulate cholesterol levels and promote healthy blood pressure.
Additionally, it has anti-inflammatory and antimicrobial properties, making it useful for gut health and immune support.
Urolithin A

Urolithin A supports cellular health, enhances mitochondrial function, and promotes muscle strength with its role in cellular rejuvenation and aging.

Urolithin A is a metabolite produced in the gut from ellagitannins found in certain fruits and nuts. It supports cellular health by enhancing mitochondrial function, which is crucial for energy production and overall cellular vitality.
Urolithin A promotes mitochondrial biogenesis and helps maintain muscle strength, which can be beneficial for aging individuals. Additionally, it has antioxidant properties that protect cells from oxidative stress and damage.
Incorporating Urolithin A into your regimen can improve cellular rejuvenation, support mitochondrial function, and promote overall muscle strength and well-being.
Haematococcus Pluvialis

Haematococcus Pluvialis Whole Algae is a potent source of astaxanthin, offering powerful antioxidant protection, supports skin health, and promotes overall well-being.

Haematococcus Pluvialis is a type of microalgae renowned for its high concentration of astaxanthin, one of the most potent antioxidants known.
Astaxanthin provides powerful protection against oxidative stress and inflammation, helping to maintain cellular health and combat premature aging.
This algae extract supports skin health by improving skin elasticity and reducing the appearance of fine lines and wrinkles. Additionally, it contributes to overall well-being by supporting cardiovascular health and enhancing energy levels.
Incorporating Haematococcus Pluvialis Whole Algae into your regimen can provide exceptional antioxidant protection, promote healthy skin, and support overall vitality.
Trans-resveratrol

Trans-Resveratrol is a potent antioxidant that supports cardiovascular health, promotes longevity, and provides anti-inflammatory benefits.

Trans-Resveratrol is a naturally occurring polyphenol found in grapes, red wine, and certain berries, known for its potent antioxidant properties. It supports cardiovascular health by reducing oxidative stress and inflammation, helping to maintain healthy blood vessels and improve circulation.
Trans-Resveratrol also has potential anti-aging effects, promoting longevity by protecting cells from damage and supporting cellular health. Additionally, it may enhance brain function and support overall well-being.
Incorporating Trans-Resveratrol into your regimen can boost cardiovascular health, promote longevity, and provide valuable antioxidant and anti-inflammatory benefits.
Spermidine HCl

Spermidine HCl supports cellular health, promotes autophagy, and may enhance longevity with its role in cellular regeneration and repair.

Spermidine HCl is a naturally occurring polyamine that supports cellular health by promoting autophagy, the process through which cells remove damaged components and regenerate. This process helps maintain cellular function and may contribute to enhanced longevity by reducing cellular aging and improving overall cellular repair mechanisms.
Spermidine HCl also has antioxidant properties that protect cells from oxidative stress and damage.
Incorporating Spermidine HCl into your regimen may support cellular health, promote effective autophagy, and contribute to improved longevity and overall well-being.
Ascophyllum Nodosum Extract

Ascophyllum Nodosum Extract, a seaweed-derived supplement, supports thyroid function, aids in weight management, and provides antioxidant protection.

Ascophyllum Nodosum Extract is derived from a type of brown seaweed and is valued for its health benefits. It supports thyroid function by providing iodine, which is essential for the production of thyroid hormones that regulate metabolism.
This extract may also aid in weight management by supporting healthy metabolism and reducing fat accumulation. Additionally, Ascophyllum Nodosum Extract offers antioxidant protection, helping to combat oxidative stress and protect cells from damage.
Incorporating this extract into your diet supports thyroid health, aids in weight management, and provides valuable antioxidant benefits.
Fucus Vesiculosus Extract

Fucus Vesiculosus Extract, derived from bladderwrack seaweed, supports thyroid health, aids metabolism, and provides antioxidant and anti-inflammatory benefits.

Fucus Vesiculosus Extract is derived from bladderwrack seaweed and is valued for its health benefits, particularly in supporting thyroid function. It provides essential iodine, which is crucial for the production of thyroid hormones that regulate metabolism.
This extract also aids in metabolic health by supporting healthy weight management and energy levels. Additionally, Fucus Vesiculosus offers antioxidant protection to combat oxidative stress and has anti-inflammatory properties that help reduce inflammation.
Incorporating this extract into your regimen can support thyroid health, aid metabolism, and provide antioxidant and anti-inflammatory benefits.

clinical trials

Setting New Standards

We set the bar high by conducting rigorous clinical trials to validate the efficacy of our products. Unlike many nutraceutical companies, we are committed to transparency and scientific validation through our ongoing trials with the San Francisco Research Institute.

clinical trial 1

Efficacy of IM8 Daily Essentials Powder

Objective:

To evaluate the effects of the Essentials Powder formula on physical parameters, fatigue, and abdominal issues. A 12-week Randomized, Controlled, Clinical Trial Evaluating the Efficacy of a Dietary Supplement Powder Formula (Daily Ultimate Essentials) in an Adult Population.

duration:

12 weeks

Participants:

60 adults aged 25-60 with BMI 18.5-30 kg/m²

Key parameters studied:

Physical activity levels
Incidence and severity of common colds and flu-like symptoms
Blood micronutrient levels (Vitamin D, B, Folate)
Quality of Life (SF-12)
Digestive symptoms (GSRS)
Gut microbiome composition
Overall physical and digestive health

Expected outcomes:

Improved energy levels, reduced fatigue, enhanced digestive health, and strengthened immune function

Please click here for full details of National Library of Medicine clinical trial

clinical trial 2

Efficacy of IM8 Longevity Supplement

Objective:

To assess the safety and efficacy of the IM8 longevity supplement in improving markers of cellular health and longevity.

duration:

12 weeks

Participants:

25 adults aged 40-70 with BMI 18.5-30 kg/m²

Key parameters studied:

Blood biomarkers of autophagy (LC3B and p62/SQSTM1 levels), mitochondrial function, and inflammation (IL6, hs-CRP, MPO)
Intracellular NAD+ levels (cellular energy metabolism)
Epigenetic biological age changes
Cognitive function (MMSE scores)
Cardiometabolic health markers (LDL cholesterol, hs-CRP levels)
Physical function tests (6-minute walk)
Changes in waist circumference and insulin resistance

Expected outcomes:

Enhanced cellular health, improved cognitive and physical function, reduced inflammation, and a potential decrease in
biological age.

Please click here for full details of National Library of Medicine clinical trial

Clinically Proven.
Feel Results in 30 days.*

Every ingredient and dosage is third-party tested. This guarantees that you know exactly what you’re putting into your body.

View Third Party Testing Results

Daily Ultimate Essentials

93%

Participants felt a noticeable boost in daily energy levels.

73%

Experienced greater endurance during physical activity.

60%

Felt less bloated and had improved digestion.

60%

Saw visible changes in the health of their hair, skin, and nails.

Clinically Proven.
Feel Results in 30 days.*

Every ingredient and dosage is third-party tested. This guarantees that you know exactly what you’re putting into your body.

View Third Party Testing Results

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*Interim Results in a 12-Week Randomized, Controlled, Clinical Trial Being Conducted by the San Francisco Research Institute. Please Click Here for FULL Details of the National Library of Medicine Trial.